From a traditional lovecraftian tale of madness to the fetishized view of vampirism "The Chosen One" tells the tragic end of dreams for Samuel and Elizabeth Wolfe, a happily expecting married couple, and their unfortunate plunge into a fiendish nightmare, after being attacked by the undead of the worst sorts. The birth, life and undeath of the couples vampire child sends Samuel into a downward spiral of twisted and horrified events. The sadistic Dr. Abraham tries to raise and study their undead baby only to be infected by his work sending the town into a murderous frenzy.